Stereoselective Synthesis of Branched Cyclopentitols by Titanium(III)-Promoted Reductive Cyclization of 4-Oxiranylaldehydes and 4-Oxiranyl Ketones Derived from Hexoses

Abstract

Titanocene chloride efficiently promotes the intramolecular reductive cross coupling of highly functionalized 4-oxiranyl­aldehydes and 4-oxiranyl ketones derived from readily available hexoses affording branched cyclopentitols with good stereoselectivity.

carbohydrates - electron transfer - epoxides - radical reactions - titanium

References

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